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The ancient medicinal plant Coleus forskohlii is the source of the compound forskolin which possesses unique biological activity. The basic mechanism of action of forskolin is the activation of an enzyme, adenylate cyclase, which increases cyclic adenosine monophosphate (cAMP) in cells.1 Cyclic AMP is perhaps the most important cell-regulating compound. Once formed it activates many other enzymes involved in diverse cellular functions.* http://www.lef.org/newsletter/2005/2005_11_15.htm#exc |
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References 1-Seamon KB, Padgett W, Daly JW. Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells. Proc Natl Acad Sci U S A. 1981 Jun;78(6):3363-7. (Full text online) |
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Supplement Facts | ||||||||||||
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Dosage and Use | ||||||||||||
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Caution | ||||||||||||
Do not use if you have prostate cancer. Do not use if you have a history of asthma or pulmonary disease. Consult your personal physician before using Forskolin if you have been diagnosed with hypertension, cardiac arrhythmia, or peptic ulcer. |
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